Sufentanil Citrate Injection, USP CII
ثبت نشده
چکیده
At intravenous dosages of ≥8 mcg/kg, sufentanil produces hypnosis and anesthesia without the use of additional anesthetic agents. A deep level of anesthesia is maintained at these dosages, as demonstrated by EEG patterns. Dosages of up to 25 mcg/kg attenuate the sympathetic response to surgical stress. The catecholamine response, particularly norepinephrine, is further attenuated at doses of sufentanil of 25 to 30 mcg/kg, with hemodynamic stability and preservation of favorable myocardial oxygen balance.
منابع مشابه
Fentanyl Citrate Injection, USP
Fentanyl Citrate Injection, USP is a potent o p i o i d ag o nis t . Each milliliter of solution contains fentanyl citrate equivalent to 50 mcg of fentanyl base, adjusted to pH 4.0 to 7.5 with sodium hydroxide. Fentanyl citrate is chemically identified as N-(1-phenethyl-4-piperidyl) propionanilide citrate (1:1) with a molecular weight of 528.60. The empirical formula is C22H28N2O • CH8O7. The s...
متن کاملDevelopment and validation of an HPLC assay for fentanyl and related substances in fentanyl citrate injection, USP.
The stability indicating properties of the USP method for the assay of fentanyl in fentanyl citrate injection were evaluated [1] by analyzing fentanyl drug substance and product after acid, hydrogen peroxide, heat, and light treatment. N-phenyl-N-(4-piperidinyl)propionamide (PPA), which is a known degradation product/process impurity of fentanyl, was not adequately resolved from the fentanyl pe...
متن کاملIntravenous Solutions with Heparin Sodium Injection Rx only 20,000 or 25,000 USP Units of Heparin Sodium in 5% Dextrose Injection Flexible Plastic Container
DESCRIPTION Intravenous solutions with heparin sodium (derived from porcine intestinal mucosa) are sterile, nonpyrogenic fluids for intravenous administration. Each 100 mL contains heparin sodium 4,000 or 5,000 USP Heparin Units; dextrose, hydrous 5 g; citric acid, anhydrous 51 mg and dibasic sodium phosphate, anhydrous 103 mg added as buffers; sodium metabisulfite added, 20 mg as an antioxidan...
متن کاملIntravenous Solutions with Heparin Sodium Rx only 1,000 USP Heparin Units/500 mL (2 USP Heparin Units/mL) or 2,000 USP Heparin Units/1,000 mL (2 USP Heparin Units/mL) in 0.9% Sodium Chloride Injection Flexible Plastic Container
DESCRIPTION Intravenous solutions with heparin sodium (derived from porcine intestinal mucosa) are sterile, nonpyrogenic fluids for intravenous administration. Each 100 mL contains heparin sodium 200 USP Heparin Units; sodium chloride, 0.9 g; citric acid, monohydrate, 40 mg and dibasic sodium phosphate, heptahydrate, 434 mg added as buffers. Each liter contains the following electrolytes: Sodiu...
متن کاملThe effect and optimal dose of sufentanil in reducing injection pain of microemulsion propofol
BACKGROUND Propofol is used as an induction and maintenance agent for general anesthesia but it can cause adverse reactions like hyperlipidemia, growth of microorganisms, and pulmonary embolisms. Microemulsion propofol was developed to avoid these side effects but incidence and severity of pain on injection is higher than with lipid emulsion propofol. We aimed to compare the effects of sufentan...
متن کامل